Growth hormone (GH) is a peptide hormone secreted by the pituitary gland that stimulates growth, cell reproduction and regeneration. As the name suggests, low growth hormone, also known as growth hormone deficiency, refers to below normal levels of this important hormone. Causes Low GH levels can be due to:

  • Damage or injury to the pituitary gland
  • Congenital conditions present at birth
  • Inflammation
  • Tumors
  • Radiation therapy
In children, the most common cause is idiopathic, meaning no specific reason is found. Symptoms The symptoms of growth hormone deficiency vary depending on age: Children
  • Slowed growth
  • Delayed puberty
  • Increased body fat
  • Muscle weakness
Adults
  • Decreased muscle mass and strength
  • Weight gain, particularly increased belly fat
  • Low energy levels and fatigue
  • Poor skin elasticity
  • Hair loss
  • Depression and emotional changes
Diagnosis Since symptoms can be vague, specific blood tests are needed to accurately diagnose the condition, usually consisting of:
  • IGF-1 and growth hormone stimulation tests
  • MRI scans to look at the pituitary gland
Treatment
  • Daily injections of synthetic growth hormone (somatropin) are the standard treatment
  • Doses are tailored to the individual
  • Treatment is lifelong, unless the condition is due to a tumor which has been successfully removed
With appropriate treatment, those with growth hormone deficiency can expect normal development through childhood and manage symptoms satisfactorily as adults. If you have any further questions, you can consult with the experts at Thrive Hormone Therapy.

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